Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. If you no longer need to take clopidogrel and have leftover medication, it’s important to dispose of it safely. This helps prevent others, including children and pets, from taking the drug by accident.
What is Plavix’s dosage?
If you’re interested in taking Plavix instead of clopidogrel, talk with your doctor. They can tell you whether Plavix comes in forms and strengths that can be used for your condition. If you have insurance, you’ll also need to check whether your plan will cover Plavix. The trial’s primary outcome was the time to first occurrence of new ischemic stroke (fatal or not), new myocardial infarction (fatal or not), or other vascular death.
My doctor said my body is a “poor metabolizer” of Plavix. What does that mean?
Embryo-fetal developmental toxicology studies were performed in pregnant rats and rabbits with doses up to 500 and 300 mg/kg/day, respectively, administered during organogenesis. Coadministration of antiplatelet agents increase the risk of bleeding due to an additive effect. Promptly evaluate https://sober-home.org/what-is-holistic-addiction-treatment/ any signs or symptoms of blood loss if patients are treated concomitantly with other antiplatelet agents [see WARNINGS AND PRECAUTIONS]. Consider the use of a parenteral antiplatelet agent in acute coronary syndrome patients requiring coadministration of morphine or other opioid agonists.
What side effects may I notice from receiving this medication?
The following lists contain some of the key side effects that may occur while taking clopidogrel. Concomitant use of strong inducers of CYP2C19 results in increased plasma concentration https://sober-house.org/cocaine-withdrawal-symptoms-timeline-and-treatment/ of the active metabolite of clopidogrel and an increase in platelet inhibition. P2Y12 inhibitors (thienopyridines), including Plavix, increase the risk of bleeding.
Precautions for Plavix
Patients also received aspirin ( mg once daily) and other standard therapies such as heparin. The use of GPIIb/IIIa inhibitors was not permitted for three days prior to randomization. Concomitant use of certain inhibitors of this enzyme results in reduced plasma concentrations of the active metabolite of clopidogrel and a reduction in platelet inhibition. Platelet inhibition by Plavix is irreversible and will last for the life of the platelet. Overdose following clopidogrel administration may result in bleeding complications.
- However, not every pharmacy stocks Plavix, the brand-name form.
- Tell your doctor all medications and supplements you use.
- (See the section above called “Allergic reaction” for more details.) However, skin rashes can also be a symptom of a dangerous condition called thrombotic thrombocytopenic purpura (TTP).
People who’ve had a stroke in the past have a higher risk of having another one. Call your doctor right away if you have any unexplained shortness of breath while you’re taking Plavix. It’s possible to have blood in your urine during Plavix treatment.
Plavix helps to prevent platelets from sticking together and forming a clot that can block an artery. The dosage and length of treatment are based on your medical condition and response to treatment. Consult your doctor for more details 10 ways to control high blood pressure without medication and about the risks of stopping early. Do not stop taking this medication without consulting your doctor. Plavix keeps your blood from coagulating (clotting) and can make it easier for you to bleed, even from a minor injury.
Ask your pharmacist any questions you have about refilling your prescription. Your donation can make a difference in the future of healthcare. Plavix may not work as well if you have certain genetic factors that affect the breakdown of this medicine in your body. Your doctor may perform a blood test to make sure Plavix is right for you. Plavix may also be used for purposes not listed in this medication guide. Clopidogrel may also be used for purposes not listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Grapefruit juice decreases the effects of your medicine, so that it may not work as well to prevent clots. Indigestion remedies called proton pump inhibitors (PPIs), such as omeprazole and esomeprazole, may reduce the effect of clopidogrel. Your doctor may prescribe daily low-dose aspirin (75mg tablets) to take together with clopidogrel.
The manufacturer does not recommend a loading dose for this use. Tests are available to identify patients who are CYP2C19 poor metabolizers [see CLINICAL PHARMACOLOGY]. The recommended dose is 75 mg per day for patient with a history of MI, stroke, or peripheral vascular disease. Many doctors may choose to add an aspirin per day along with the Plavix dose in both non-ST elevation and ST elevation MIs as well as to stroke and peripheral vascular disease patients.
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